|Location||Western Sydney University, School of Medicine|
|Eligibility||Open to international applicants|
Rod and cone interactions in the mouse electroretinogram
The mammalian retina functions over a very wide range of light intensities, from dim starlight to bright Australian sunlight. It does this by using two main photoreceptive systems: rods for dim light intensities, and cones for bright light intensities. However, these two systems are intrinsically linked within the circuitry of the retina and can influence the function of one another. This project will investigate the interaction between rod and cone neural pathways by measuring the mouse electroretinogram in a variety of transgenic mouse models. Fundamental insights into the function of rod and cone systems will be analysed including temporal properties, spectral sensitivities and light adaptation. The main technique involved will be electroretinogram but immunohistochemistry and single-cell electrophysiology will complement this technique. No technical experience is necessary as full training will be given, however candidates must have an interest in neuroscience/retinal biology and a life sciences/medical background.
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