|Location||University of South Australia, Centre for Cancer Biology|
|Eligibility||Open to international applicants|
PhD scholarship in cell mechanics/quantitative imaging/computational modeling.
Mechanochemical basis of cell polarity.
Understanding how polarity is defined and initiated in epithelial
tissues is essential knowledge that will inform
efforts to manipulate epithelia in a variety of disciplines from tissue engineering to regenerative biology and
contribute to our appreciation of how epithelial architecture and physiology is generated.
In this project we will combine micropatterned substrates, measurements
of rheological properties of the actin cortex of cells by using single
molecule imaging approaches, signalling biosensors and computational
modeling to investigate the
mechanochemical basis of cell polarity and how this leads to the formation of signalling zones within the cell cortex.
This project aligns to other projects within the lab described at:
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