|Location||University of Technology Sydney, Plant Functional Biology and Climate Change Cluster|
|Eligibility||Open to international applicants|
Screening for chemotherapeutic scaffolds from toxin-producing microalgae
The projects aim is to identify potential molecules for use as therapeutic agents or as drug leads from toxin-producing microalgae. The study will involve culturing and maintenance of algal cell cultures, bioactivity assays, isolation and characterization of metabolites using chromatography, mass spectrometry and NMR spectroscopy. The project will also include in silico molecular modeling, rational drug design/improvements to produce novel molecules.
The Climate Change Cluster (C3) at UTS is a world-class integrated research institute delivering research excellence in the area of food and energy security, sustainability, ecological resilience and global health. The successful applicant for this strategic PhD position will work within the Algal Biosystems team.
Desirable Skills and Qualifications:
Ø H1 Honours or Master’s degree and/or published work or research experience.
Ø Background in natural products chemistry, analytical chemistry, in silico molecular modelling and in vitro biological assays
Ø Experience with isolation of organic compounds using column chromatography and HPLC
Ø Experience with identification of organic compounds by spectroscopic methods such as NMR, mass spectrometry and LC-MS.
Ø Prior expertise in extraction, isolation, and characterisation of molecules from natural
Ø Good communication skills, a collaborative outlook and ability to function well in a multi-disciplinary research team.
Overseas applications are welcomed (with current IELTS assessments), but Australian and New Zealand permanent residents will be preferred. Successful applicant must commence their studies no later than 31 August 2017 (Visa approved).
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